8 research outputs found
Fiberless, Multi-Channel fNIRS-EEG System Based on Silicon Photomultipliers: Towards Sensitive and Ecological Mapping of Brain Activity and Neurovascular Coupling
Portable neuroimaging technologies can be employed for long-term monitoring of neurophysiological and neuropathological states. Functional Near-Infrared Spectroscopy (fNIRS) and Electroencephalography (EEG) are highly suited for such a purpose. Their multimodal integration allows the evaluation of hemodynamic and electrical brain activity together with neurovascular coupling. An innovative fNIRS-EEG system is here presented. The system integrated a novel continuous-wave fNIRS component and a modified commercial EEG device. fNIRS probing relied on fiberless technology based on light emitting diodes and silicon photomultipliers (SiPMs). SiPMs are sensitive semiconductor detectors, whose large detection area maximizes photon harvesting from the scalp and overcomes limitations of fiberless technology. To optimize the signal-to-noise ratio and avoid fNIRS-EEG interference, a digital lock-in was implemented for fNIRS signal acquisition. A benchtop characterization of the fNIRS component showed its high performances with a noise equivalent power below 1 pW. Moreover, the fNIRS-EEG device was tested in vivo during tasks stimulating visual, motor and pre-frontal cortices. Finally, the capabilities to perform ecological recordings were assessed in clinical settings on one Alzheimerâs Disease patient during long-lasting cognitive tests. The system can pave the way to portable technologies for accurate evaluation of multimodal brain activity, allowing their extensive employment in ecological environments and clinical practice
A novel technique for the CMRR improvement in a portable ECG system
This paper presents a new technique to improve the quality of the ECG signals, increasing the Common Mode Rejection Ratio (CMRR). We developed a portable wireless Bluetooth ECG system able to acquire 12 leads, communicating with Smartphones and PCs. Many experiments have been made for measuring CMRR decay due to the difference on skin-electrodes impedances, the asymmetries of the amplifiers input stages and external components. Using some digital potentiometers, the system is able to compensate for these, increasing the CMRR of about 18 dB
Exploring FPGAâBased LockâIn Techniques for Brain Monitoring Applications
Functional nearâinfrared spectroscopy (fNIRS) systems for eâhealth applications usually suffer from poor signal detection, mainly due to a low endâtoâend signalâtoânoise ratio of the electronics chain. Lockâin amplifiers (LIA) historically represent a powerful technique helping to improve performance in such circumstances. In this work a digital LIA system, based on a ZynqÂź field programmable gate array (FPGA) has been designed and implemented, in an attempt to explore if this technique might improve fNIRS system performance. More broadly, FPGAâbased solution flexibility has been investigated, with particular emphasis applied to digital filter parameters, needed in the digital LIA, and its impact on the final signal detection and noise rejection capability has been evaluated. The realized architecture was a mixed solution between VHDL hardware modules and software modules, running within a microprocessor. Experimental results have shown the goodness of the proposed solutions and comparative details among different implementations will be detailed. Finally a key aspect taken into account throughout the design was its modularity, allowing an easy increase of the input channels while avoiding the growth of the design cost of the electronics system
Effects of Plk1 depletion on centrosome duplication and cell cycle progression in HCT116 tumor cells
FLUMO: FLexible Underwater MOdem
The last years have seen a growing interest in underwater acoustic communications because of its applications in marine research, oceanography, marine commercial operations, the offshore oil industry and defense. High-speed communication in the underwater acoustic channel has been challenging because of limited bandwidth, extended multipath, refractive properties of the medium, severe fading, rapid time variation and large Doppler shifts. In this paper, we show an implementation of a flexible Software-Defined Acoustic (SDA) underwater modem, where modulation parameters are completely tunable to optimize performance. In particular, we develop the system architecture following two key ideas. First, the modulation/demodulation part runs fully in software and is completely decoupled from the rest of the system. The system can be used to send/receive modulated signals from different system and, on the other side, it can be used to modulate signals that are sent from different system. Second, we provide to the users a flexible and tunable system where the different communication parameters can be adjusted in order to reach the best performance in every scenario. The proposed modem, that also supports the JANUS standard, has been validated experimentally in two different controlled testbeds and also through the Watermark simulator, which provides a realistic and repeatable co-simulation environment
Consumo de crĂas de didĂ©lfidos por Micoureus paraguayanus (Didelphimorphia: Didelphidae) en el sudeste de Brasil
In a study aiming to describe the diet of Micoureus paraguayanus in a southeastern Brazilian Cerrado (savannah-like) remnant, we found young didelphid remains in fecal samples from live-trapped adults. These findings uncovered either events of scavenging on dead young didelphids or infanticide adding to the knowledge on the dietary breadth and behavioral ecology of M. paraguayanus. © SAREM, 2010